About Our Xtreme Hike

We can’t wait to bring the CF community together for the 2022 South Carolina Xtreme Hike! This year’s route will take hikers along the beautiful Foothills Trail, with highlights including the nationally designated "Wild and Scenic" Chattooga River and Whitewater Falls, the highest waterfall east of the Rockies. Hikers can choose their own adventure, with mileage options ranging from 22 to 30 miles in one day.

The Hiker's Journey

All hikers will enjoy accommodations for three days and two nights at Lakeside Lodge Clemson. This includes an energizing, pre-hike pasta party, pre-hike breakfast, post party dinner and a “Victory” breakfast on Sunday. As participants prepare for the physical challenge, hikers are encouraged to raise a $2,500 fundraising minimum through their personal and social media campaigns.

Register. Register to participate in-person or virtually in this year’s Xtreme Hike event and help us stay the course and advance our mission. Stay up to date on how our chapter plans to safely bring the community together and make CF stand for Cure Found by registering today.

The journey of participation includes:

  • 3 month training plan with regular group hikes
  • Accommodations for 3 days and 2 nights
  • Transportation to and from the Start/Finish
  • Fully-stocked rest stops along the trail
  • Official Xtreme Hike wicking shirt
  • Pre-hike pasta party
  • Prior to sunrise hike breakfast
  • Pre-hike pasta party
  • Victory breakfast

Recruit. Recruit others to participate with you! Friends, family, and co-workers can join you virtually from anywhere in the world.

Fundraise. Fundraise online by leveraging the tools in the Participant Center, the Fight CF mobile app, and Fundraise on Facebook to reach your goal. Create a virtual passion fundraising event by developing a fundraising event through your favorite hobby, activity, or passion.

Share your Journey Wear an Xtreme Hike shirt, team shirt, or your Cystic Fibrosis Foundation branded apparel, while you hike with us or on your own local trail or within your neighborhood\! Track your activity on the Fight CF mobile app so you can hike with others participating in the event and across the country. Share how you decided to hike this year by sharing your story and posting a selfie on Facebook, Twitter, and Instagram. Make sure to tag us on instagram: @cff_sc or Facebook: @CFFFSouthCarolina.

Celebrate.  Join us after the hike to celebrate with your team, or join us online for a virtual celebration. Contact Annie at acarenbauer@cff.org to learn more.

Thank you Sponsors

We want to thank our generous national sponsors - gold national sponsor, AbbVie, and our silver national sponsors, Nestle Health Sciences, Vertex, Gilead, and Genentech. Thank you, American Airlines, our Outstanding Corporate Supporter.

We also want to thank our local sponsors who continue to help advance our mission.


In lieu of cash, we ask that you make all payments/contributions to the CF Foundation with a credit card or check. We accept all major credit cards. Thank you for understanding.

Events may be subject to change at any time, based on health concerns, including concerns based on guidance from the Centers for Disease Control and Prevention and local health officials. In these instances when events are moved to a virtual format, sponsorship benefits may be adjusted to suit the virtual format.