Cystic fibrosis (CF) is an inheritable progressive disease caused by mutations in
the CFTR gene
, which leads to a thick mucus buildup in the lungs, pancreas, liver, and intestine. This can cause inflammation and damage, leading to scarring (fibrosis).
CF is caused by a mutation in the
gene, which provides instructions to build the CTFR protein, a channel in the cell membrane that regulates the movements of negatively charged particles, known as chloride ions, in and out of cells. There are more than 1,700 known mutations in the
gene that can cause CF and disrupt the normal function of the chloride channels.
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IMPORTANT NOTE ON ATTENDANCE AT FOUNDATION EVENTS:
Updated June 15, 2022. To reduce the risk of COVID-19 the Foundation is taking steps to host safe events for our community. Please be advised that events may be subject to change at any time based on guidance from the Centers for Disease Control and Prevention and local health officials.
To minimize the risk of COVID-19 infection, we ask that attendees at CF Foundation events follow these steps:
FOR YOUR SAFETY AND THE SAFETY OF OTHERS: